Levistolide A

Overview

Levistolide A is an apoptosis inducer and a PEDV virus inhibitor. Levistolide A can induce apoptosis in colon cancer cells and suppress the replication of porcine epidemic diarrhea virus ( PEDV ) by promoting ROS generation. Levistolide A activates peroxisome proliferator-activated receptor γ ( PPARγ ) in N2a/APP695swe cells and reduces excessive phosphorylation of tau through the GSK3α/β pathway, improving symptoms in Alzheimer’s mice. Levistolide A improves kidney damage in 5/6 nephrectomy (Nx) mice by inhibiting the RAS , TGF-β1/Smad , and MAPK pathways.

Application

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Product Information

• Catalog No.: HY-N1472
• CAS No.: 88182-33-6
• Molecular Formula: C24H28O4
• Molecular Weight: 380.48
• Purity: 99.34%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (6.57 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source