Pochonin D

Overview

Pochonin D ((+)-Pochonin D) is an inhibitor of heat shock protein 90 ( Hsp90 ) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90 , affects the homeostasis, folding and assembly processes of viral proteins , and reduces the replication capacity of viruses. Pochonin D is a copper ion carrier that can induce cuproptosis in triple-negative breast cancer cells by targeting PRDX1 . Pochonin D reduces the infiltration of inflammatory cells, decreases the secretion of inflammatory cytokines such as TNF-α and IL-1β, and alleviates inflammatory responses. Pochonin D is a promising candidate for research on human rhinovirus (HRV) infection and cancer .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Parasitic Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Enterovirus | Products > Signaling Pathways > Cuproptosis | Products > Signaling Pathways > HSP | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-N14780
• CAS No.: 544712-82-5
• Molecular Formula: C18H19ClO5
• Molecular Weight: 350.79
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source