BX795 (Standard)

Overview

BX795 (Standard) is the analytical standard of BX795 ( HY-10514 ). This product is intended for research and analytical applications. BX795 is a potent and selective inhibitor of PDK1, with an IC 50 of 6 nM. BX795 is also a potent and relatively specific inhibitor of TBK1 and IKKε , with an IC 50 of 6 and 41 nM, respectively. BX795 blocks phosphorylation of S6K1, Akt , PKCδ , and GSK3β, and has lower selectivity over PKA , PKC , c-Kit , GSK3β etc. BX795 modulates autophagy .

Application

Products | Products > Signaling Pathways > Others | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > PDK-1 | Products > Signaling Pathways > IKK | Products > Signaling Pathways > Autophagy

Product Information

• Catalog No.: HY-10514R
• CAS No.: 702675-74-9
• Molecular Formula: C23H26IN7O2S
• Molecular Weight: 591.47
• Purity: 98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source