Eupolauridine

Overview

Eupolauridine (Canangine) is a selective DNA topoisomerase II inhibitor with IC 50 values of 20 μM for fungal topoisomerase I and 33 μM for human topoisomerase I . Eupolauridine exerts antifungal activity by inhibiting the catalytic activity of topoisomerase II and stabilizing its cleavage complex with DNA, leading to DNA damage. Eupolauridine is promising for research of fungal infectious diseases.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Fungal

Product Information

• Catalog No.: HY-N15319
• CAS No.: 58786-39-3
• Molecular Formula: C14H8N2
• Molecular Weight: 204.23
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source