RBM1-151

Overview

RBM1-151, a 1-deoxy derivative and vinilog of RBM14-C12 ( HY-150163 ), as a fluorogenic substrate of Amidase s ( HY-P2736 ) (E x /E m ). RBM1-151 is hydrolyzed by acid ceramidase (AC) (( app K m = 7.0 μM; app V max = 99.3 nM/min), N-acylethanolamine-hydrolyzing acid amidase ( app K m = 0.73 μM; app V max = 0.24 nM/min), and fatty Acid amide hydrolase ( FAAH ) ( app K m = 3.6 μM; app V max = 7.6 nM/min) but not by other ceramidases. RBM1-151 is applicable for basic biological studies of lipid amidase function, as well as potential diagnostic/prognostic evaluations of diseases involving dysregulated AC, NAAA, or FAAH (Farber disease, cancer ).

Application

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Product Information

• Catalog No.: HY-N15826
• CAS No.: 3077081-47-8
• Molecular Formula: C28H41NO5
• Molecular Weight: 471.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source