Calicheamicin

Overview

Calicheamicins are a class of enediyne antitumor antibiotics derived from the bacterium Micromonospora echinospora, The main component is calicheamicin γ1. It has strong anti-Gram-positive bacteria activity and anti-tumor effect. Source summary: Calicheamicin is a DNA-cleaving ADC cytotoxin that induces double-strand breaks, widely used in antibody-drug conjugate payloads.

Application

Products > Drug Discovery > Inhibitor | Products > Drug Discovery > Inhibitor | Infection | Antibiotic

Product Information

• Catalog No.: B0084-470810
• CAS No.: 108212-75-5
• Molecular Formula: C55H74IN3O21S4
• Molecular Weight: 1368.35
• Purity: ≥95% by HPLC
• Storage: Store at 2-8°C for short term (days to weeks) or -20°C for long term (months to years)
• Solubility: Soluble in DMSO, not in water

Source

Original product source