ER-Laurdan

Overview

ER-Laurdan is a derivative of the membrane-permeable fluorescent probe Laurdan ( HY-D0080 ) that targets the endoplasmic reticulum (ER) . As a membrane fluidity reporter, ER-Laurdan specifically localizes to the ER luminal membrane, and exhibits a prominent solvatochromic response to fluidity changes caused by membrane packing and exogenous saturated fatty acid stress. ER-Laurdan shows no overlapping localization with mitochondria, enables quantitative analysis of ER membrane fluidity via generalized polarization ratio measurement, and allows automatic signal masking with the help of ER markers. With high specificity and quantitative capability, ER-Laurdan serves as an important tool for investigating metabolic disorders and associated changes in the physical properties of cell membranes.

Application

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Product Information

• Catalog No.: HY-N16308
• CAS No.: 3091879-77-2
• Molecular Formula: C54H80F5N3O13
• Molecular Weight: 1074.22
• Purity: 99.98%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source