Aspergillusidone F is a Depsidone and antibacterial agent. Aspergillusidone F can be isolated from a marine fungus Aspergillus unguis . Aspergillusidone F potently inhibits Aromatase with an IC 50 of 0.5 μM. Aspergillusidone F exhibits antibacterial activity against Pseudomonas aeruginosa and Methicillin ( HY-121544 )-resistant Staphylococcus aureus . Aspergillusidone F exhibits potent larvicidal activity against Artemia salina larvae, with an LC 50 value of 12.8 μM. Aspergillusidone F exhibits anticancer activity against intrahepatic cholangiocarcinoma, non-small cell lung cancer , and acute lymphoblastic leukemia.
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