Ilekudinol B is an inhibitor of ACAT and PTP1B , with an IC 50 of 5.3 μM and a K i of 11.6 μM against human PTP1B. Ilekudinol B inhibits the classical pathway of the complement system , with an IC 50 of 51 μM. Ilekudinol B inhibits TNF-α-induced cellular IL-8 secretion, promotes glucose uptake in skeletal muscle myotubes, and acts as an insulin mimetic and insulin sensitizer. Ilekudinol B can be used in research related to type 2 diabetes, obesity, and inflammatory diseases.
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