Vitedoamine A

Overview

Vitedoamine A is a Phenylnaphthalene-type lignan alkaloid. Vitedoamine A can be isolated from Vitex negundo . Vitedoamine A inhibits the activity of IKKβ with an IC 50 value of 39 μM. Vitedoamine A could inhibit the transcriptional activity of NF-κB , and suppress the production of NO and reduce the expressions of inflammatory cytokines ( IL-1β , IL-6 , and TNF-α ). Vitedoamine A inhibits the phosphorylation of IKKα/β and p65 , and prevents the degradation of IκBα . Vitedoamine A possesses anti-rheumatoid arthritis capacity.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Multiple Sclerosis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > IKK | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > NO Synthase | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-N17353
• CAS No.: 819861-41-1
• Molecular Formula: C20H17NO5
• Molecular Weight: 351.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source