Regiafuran C

Overview

Regiafuran C is a compound with both TGF-βRI inhibitory and anti-fibrotic activities. Regiafuran C effectively inhibits renal fibrosis by binding to TGF-βRI and interfering with the TGF-β/Smad and Wnt/β-catenin signaling pathways. Regiafuran C also exhibits free radical scavenging activity, but shows no anti-inflammatory activity in PGE2 competitive enzyme immunoassays. The ability of Regiafuran C to specifically block the Smad3-TGF-βRII interaction and inhibit fibrotic processes allows its use in renal fibrosis research. - Mechanism of Action & Protocol.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Others | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > TGF-β Receptor

Product Information

• Catalog No.: HY-N17639
• CAS No.: 2059921-60-5
• Molecular Formula: C25H28O5
• Molecular Weight: 408.49
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source