Tetrandrine 2'-N-β-oxide is an anti-hyperglycemic dibenzylisoquinoline alkaloid. At a dose of 1 mg/kg, Tetrandrine 2'-N-β-oxide can reduce hyperglycemia levels in streptozotocin ( HY-13753 )-induced diabetic mice to nearly 50% of their original levels. Tetrandrine 2'-N-β-oxide is primarily used in research related to the anti-hyperglycemic of type 2 diabetes.
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