WYE-103914 is an orally active α7 nAChR ( EC 50 = 0.49 µM for rat α7 nAChR , EC 50 = 0.57 µM for human α7 nAChR ) agonist. WYE-103914 exhibits the ability to enhance memory in multiple cognitive models. WYE-103914 is used in combination with antipsychotic drugs. WYE-103914 can be used for research on schizophrenia.
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