Norkurarinol

Overview

Norkurarinol is a prenylated flavonoid. Norkurarinol can be isolated from Sophora flavescens . Norkurarinol potently inhibits mushroom Tyrosinase DOPA oxidase activity with an IC 50 of 2.1 μM. Norkurarinol inhibits poly(I:C)-induced NF-κB / AP-1 activation. Norkurarinol inhibits pro-inflammatory cytokines ( TNF-α , IL-6 ). Norkurarinol inhibits phosphorylation of p38 , JNK , and ERK1/2 . Norkurarinol increases phosphorylation of IRF3 . Norkurarinol has antiviral activity against Rotavirus KJ56-1

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Infection | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > JNK | Products > Signaling Pathways > ERK | Products > Signaling Pathways > Tyrosinase | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > AP-1

Product Information

• Catalog No.: HY-N18197
• CAS No.: 52483-01-9
• Molecular Formula: C25H30O7
• Molecular Weight: 442.50
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source