Edpetiline is an anti-inflammatory agent. Edpetiline inhibits the phosphorylation of IκB , nuclear transcription/translocation of NF-κB p65 , as well as the phosphorylation of p38 MAPK and ERK MAPK . Edpetiline reduces intracellular ROS levels, inhibits the expression of TNF-α , IL-6 , iNOS , COX-2 , and promotes the expression of IL-4 . Edpetiline is applicable to the research of diseases associated with inflammation and oxidative stress.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > COX | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > p38 MAPK | Products > Signaling Pathways > TNF Receptor
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