Gamma-Mangostin

Overview

Gamma-Mangostin is a novel competitive 5-hydroxytryptamine 2A (5-HT2A) receptor antagonist and potent epoxidase 2 ( COX-2 ) inhibitor, as well as a transthyroxin protein (TTR) profibrosis inhibitor. Gamma-Mangostin binds to the thyroxine (T4)-binding sites and stabilized the TTR tetramer. Gamma-Mangostin inhibits [3 H ] spiperone binding to cultured rat aortic myocytes ( IC 50 =3.5 nM) and reduces The perfusion pressure response of rat coronary artery to 5-HT2A ( IC 50 =0.32 μM). Gamma-Mangostin has anti-inflammatory, antibacterial , antioxidant and anticancer activities, and can be used in the study of metabolic disorders such as diabetes.

Application

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Product Information

• Catalog No.: HY-N1957
• CAS No.: 31271-07-5
• Molecular Formula: C23H24O6
• Molecular Weight: 396.43
• Purity: 99.91%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.31 mM); Clear solution
• Availability: In-stock

Source

Original product source