Gaultherin (Standard) is the analytical standard for Gaultherin ( HY-N1965 ). Gaultherin is an orally active non-steroidal anti-inflammatory agent. Gaultherin selectively inhibits NF-κB , MAPK , COX-2 ( IC 50 = 0.35 mg/mL), LOX ( IC 50 = 0.56 mg/mL) and HYAL ( IC 50 = 28.58 μg/mL) to exert anti-inflammatory, antipyretic and analgesic effects. Gaultherin exhibits modest direct antioxidant capacity, greater in cell-based models. Gaultherin does not affect COX-1 so that avoids the common gastrointestinal side effects of Aspirin ( HY-14654 ).
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