5,7-Dihydroxychromone

Overview

5,7-Dihydroxychromone is a flavonoid compound with antioxidant properties. 5,7-Dihydroxychromone induces Nrf2 nuclear translocation, increases Nrf2 /ARE binding activity, and up-regulates Nrf2 -dependent antioxidant genes HO-1 , NQO1 , GCLc . 5,7-Dihydroxychromone attenuates excessive ROS generation, inhibits activated caspase-3 , caspase-9, cleaved PARP expression, and prevents neuronal apoptosis and cell death . 5,7-Dihydroxychromone increases LXRα and PPARγ mRNA expression, induces preadipocyte differentiation, and regulates blood glucose levels . 5,7-Dihydroxychromone inhibits radial growth of soil pathogenic fungi, radicle elongation of select seedlings, and transiently inhibits Bradyrhizobium sp. growth in high mannitol medium. 5,7-Dihydroxychromone can be used for the research of Parkinson’s disease , type 2 diabetes mellitus and pathogenic fungal infection.

Application

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Product Information

• Catalog No.: HY-N1970
• CAS No.: 31721-94-5
• Molecular Formula: C9H6O4
• Molecular Weight: 178.14
• Purity: 99.94%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (14.03 mM); Clear solution
• Availability: In-stock

Source

Original product source