(Z)-Onjisaponin B

Overview

(Z)-Onjisaponin B ((Z)-Senegin III) is a derivative of Onjisaponin B ( HY-N2099 ). Onjisaponin B is an orally active natural product derived from Polygala tenuifolia . Onjisaponin B inhibits NF-κB p65 . Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin . Onjisaponin B reduces β-amyloid (Aβ) production. Onjisaponin B reduces radiation-induced cell apoptosis . Onjisaponin B has anti-oxidant and anti-inflammatory activities. Onjisaponin B can be used for neurological disease and radiation injury study, and its metabolite tenuifolin (TF) can enter the brain through the BBB.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-N2099A
• CAS No.: 162681-53-0
• Molecular Formula: C75H112O35
• Molecular Weight: 1573.67
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source