N-Nornuciferine

N-Nornuciferine
  • CAS No.:4846-19-9
  • Grade:99.92%
  • Formula:C18H19NO2
  • M.W.:281.35
  • Solvent:≥ 2.5 mg/mL (8.89 mM); Clear solution

Overview

N-Nornuciferine is an orally active, blood-brain barrier-permeable CYP2D6 inhibitor, with an IC 50 of 3.76 μM and a K i of 2.34 μM against human CYP2D6 . N-Nornuciferine also acts as a BChE inhibitor, showing an IC 50 of 5.6 μM in mice . N-Nornuciferine can be used in the research of neurological-related diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Cholinesterase (ChE)

Product Information

  • Catalog No.: HY-N2129
  • CAS No.: 4846-19-9
  • Molecular Formula: C18H19NO2
  • Molecular Weight: 281.35
  • Purity: 99.92%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Solubility: ≥ 2.5 mg/mL (8.89 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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