Psammaplin A

Overview

Psammaplin A is a marine metabolite. Psammaplin A is a selective HDAC1 ( IC 50 : 45 nM), DNA methyltransferases ( IC 50 : 18.6 nM) and aminopeptidase N (APN) ( IC 50 : 18 μM) inhibitor. Psammaplin A also inhibits DNA topoisomerase and farnesyl protein transferase . Psammaplin A is a PPARγ activator and induces apoptosis . Psammaplin A has antitumor and anti-inflammatory activities. Psammaplin A has antibacterial activity against Gram-positive bacteria and inhibits DNA synthesis and DNA gyrase activity. Psammaplin A inhibits angiogenesis.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Aminopeptidase | Products > Signaling Pathways > Farnesyl Transferase | Products > Signaling Pathways > PPAR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > DNA Methyltransferase

Product Information

• Catalog No.: HY-N2150
• CAS No.: 110659-91-1
• Molecular Formula: C22H24Br2N4O6S2
• Molecular Weight: 664.39
• Purity: 96.0%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
• Availability: In-stock

Source

Original product source