Swertiajaponin

Swertiajaponin
  • CAS No.:6980-25-2
  • Grade:98.53%
  • Formula:C22H22O11
  • M.W.:462.40
  • Solvent:≥ 1.25 mg/mL (2.70 mM); Clear solution

Overview

Swertiajaponin is a tyrosinase inhibitor , forms multiple hydrogen bonds and hydrophobic interactions with the binding pocket of tyrosinase , with an IC 50 of 43.47 μM. Swertiajaponin also inhibits oxidative stress-mediated MAPK/MITF signaling, leading to decrease in tyrosinase protein level. Swertiajaponin suppresses melanin accumulation and exhibits strong anti-oxidative activity.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Tyrosinase | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

  • Catalog No.: HY-N2204
  • CAS No.: 6980-25-2
  • Molecular Formula: C22H22O11
  • Molecular Weight: 462.40
  • Purity: 98.53%
  • Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
  • Solubility: ≥ 1.25 mg/mL (2.70 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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