Nodakenetin

Overview

Nodakenetin is an orally active Wnt/β-catenin pathway activator. Nodakenetin reduces the level of DKK1 , and upregulates c-Myc , cyclin D1 and survivin . Nodakenetin induces osteoprogenitor cell differentiation, upregulates bone formation biomarkers and prevents bone microstructure degeneration. Nodakenetin induces irritant skin reactions. Nodakenetin improves bone microstructure and histomorphometric parameters in osteoporotic mouse models. Nodakenetin can be used for osteoporosis-related research.

Application

Products | Products > Disease Areas > Osteoporosis | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Mineral Metabolism | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > c-Myc | Products > Signaling Pathways > Survivin

Product Information

• Catalog No.: HY-N2276
• CAS No.: 495-32-9
• Molecular Formula: C14H14O4
• Molecular Weight: 246.26
• Purity: 99.66%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (10.15 mM); Clear solution
• Availability: In-stock

Source

Original product source