L-Quebrachitol is a methoxy analog of inositol that can be isolated from plants . L-Quebrachitol has free-radical scavenging, gastroprotection, anti-platelet aggregation and anti-diabetic activity. L-Quebrachitol promotes osteoblastogenesis by uppregulation of BMP-2, runt-related transcription factor-2 ( Runx2 ), MAPK ( ERK , JNK , p38α ), and Wnt/β-catenin signaling pathway.
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