Methyl isoeugenol

Overview

Methyl isoeugenol is an orally active, blood-brain barrier-permeable isoeugenol-type eugenol analog. Methyl isoeugenol promotes the nuclear translocation of Nrf2 , upregulates the expressions of HO-1 , NQO1 and SOD , and reduces the expression level of MDA . Methyl isoeugenol decreases the nuclear translocation of NF-κB . Methyl isoeugenol inhibits NLRP3 inflammasome-mediated pyroptosis . Methyl isoeugenol reduces cerebral infarction volume and regulates the M1/M2 phenotypic balance of microglia. Methyl isoeugenol can be used for the research of cerebral ischemia-reperfusion injury.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Pyroptosis | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Quinone Reductase | Products > Signaling Pathways > SOD

Product Information

• Catalog No.: HY-N2439
• CAS No.: 93-16-3
• Molecular Formula: C11H14O2
• Molecular Weight: 178.23
• Purity: 98.11%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source