Methylophiopogonone A (Standard)

Overview

Methylophiopogonone A (Standard) is the analytical standard of Methylophiopogonone A ( HY-N2441 ). This product is intended for research and analytical applications. Methylophiopogonone A is a homoisoflavonoid compound found in the tuberous roots of Ophiopogon japonicus . Methylophiopogonone A inhibits lipopolysaccharide-induced NO production in mouse microglia with an IC 50 of 19.2 μM. Methylophiopogonone A blocks the proliferation of LX-2 hepatic stellate cells and downregulates TGF-β1-induced expressions of type I collagen and α-SMA . Methylophiopogonone A blocks RELA/EGFR-mediated hepatic stellate cell activation, inhibits the MAPK12 pathway to reduce extracellular matrix accumulation, and simultaneously suppresses inflammatory signal transduction. Methylophiopogonone A can be used in studies related to chronic hepatitis B-associated hepatic fibrosis and neuroinflammation.

Application

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Product Information

• Catalog No.: HY-N2441R
• CAS No.: 74805-90-6
• Molecular Formula: C19H16O6
• Molecular Weight: 340.33
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source