Cochinchinenin C

Overview

Cochinchinenin C is a GLP-1R agonist that binds to the extracellular domain of the receptor via hydrophobic interactions and hydrogen bonds, and promotes glucose-dependent insulin secretion from pancreatic β-cells. Cochinchinenin C also increases intracellular cAMP and ATP levels. At low concentrations, Cochinchinenin C binds to human serum albumin, alters its microenvironment, and induces dominant static fluorescence quenching. Cochinchinenin C shows almost no cytotoxicity to pancreatic β-cells, and exerts a synergistic effect with Loureirin A ( HY-N1505 ) when binding to human serum albumin. Cochinchinenin C has been widely used in studies of type 2 diabetes, Helicobacter pylori infection , thrombotic diseases, and other conditions.

Application

Products | Products > Disease Areas > Blood Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Helicobacter Pylori Infection | Products > Disease Areas > Platelet Disease | Products > Disease Areas > Type 2 Diabetes | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Gastric Disease | Products > Disease Areas > Bacterial Infection | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Metabolic Disease | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > GLP Receptor

Product Information

• Catalog No.: HY-N2452
• CAS No.: 956103-79-0
• Molecular Formula: C33H34O7
• Molecular Weight: 542.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source