Marmin

Overview

Marmin is a histamine receptor inhibitor and tracheal smooth muscle relaxant. Marmin antagonizes histamine- and methacholine-induced contraction of tracheal smooth muscle. Marmin inhibits histamine release from mast cells, and also blocks extracellular calcium influx via voltage-dependent calcium channels as well as calcium release from intracellular calcium stores, thereby effectively inhibiting calcium-mediated smooth muscle contraction. Marmin slightly enhances the relaxant effect of isoprenaline, and induces epithelial-dependent tracheal smooth muscle relaxation independent of nitric oxide , cGMP or β 2 -adrenergic pathways through the release of prostaglandin E 2 .

Application

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Product Information

• Catalog No.: HY-N3320
• CAS No.: 14957-38-1
• Molecular Formula: C19H24O5
• Molecular Weight: 332.39
• Purity: 99.40%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.52 mM); Clear solution
• Availability: In-stock

Source

Original product source