rel-Cleroindicin F

Overview

rel-Cleroindicin F (Rengyolone) is a cyclohexyl acetyl compound that can be isolated from the fruit of forsythia and has anti-inflammatory activity. It strongly inhibits the production of nitric oxide (NO) and tumor necrosis factor-alpha ( TNF-α ). rel-Cleroindicin F does this by downregulating the activity of NF-κB and NF-κB kinases in RAW 264.7 cells stimulated by LPS ( HY-D1056 ), thus inhibiting the expression of inducible nitric oxide synthase ( NO Synthase ) and nitric oxide production.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TNF Receptor | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > NO Synthase

Product Information

• Catalog No.: HY-N3602A
• CAS No.: 94535-01-0
• Molecular Formula: C8H10O3
• Molecular Weight: 154.16
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source