Dehydroabietinol

Overview

Dehydroabietinol is a SYK inhibitor with an IC 50 of 46.4 μM. Dehydroabietinol inhibits the growth of Trypanosoma cruzi epimastigotes, Leishmania braziliensis promastigotes and Leishmania infantum promastigotes. Dehydroabietinol indirectly inhibits the growth of Plasmodium falciparum , alters the erythrocyte membrane, and induces spherostomatocyte transformation and endovesicle formation. Dehydroabietinol can be used in studies related to immune-mediated diseases, Chagas disease, leishmaniasis and malaria.

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Plasmodium Infection | Products > Disease Areas > Leishmania Infection | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Infection | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Syk

Product Information

• Catalog No.: HY-N3702
• CAS No.: 3772-55-2
• Molecular Formula: C20H30O
• Molecular Weight: 286.45
• Purity: 98.90%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source