Guaiol

Overview

Guaiol is a sesquiterpenoid alcohol with oral activity found in various traditional Chinese medicines, exhibiting biological activities such as anti-proliferative, autophagy-promoting, insecticidal, anti-anxiety, anti-inflammatory, diuretic, and blood pressure-lowering effects. Guaiol induces apoptosis in non-small cell lung cancer cells by regulating the stability of RAD51 through autophagy modulation. Guaiol can also act directly on parasites, inhibiting their growth by affecting the kinetoplast, mitochondrial matrix and plasma membrane of the promastigotes. Guaiol kills amastigotes at an IC 50 of 0.01 µg/mL. Guaiol can be used in research related to cancer , infections, cardiovascular diseases, and inflammatory conditions [4] For research use only. We do not sell to patients. Purity: 99.67% CAS No.: 489-86-1 Formula: C 15 H 26 O Molecular Weight: 222.37 Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month Data Sheet (281 KB) SDS COA

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Parasitic Infection | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Infection | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Research Areas > Cardiovascular Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > RAD51

Product Information

• Catalog No.: HY-N3980
• CAS No.: 489-86-1
• Molecular Formula: C15H26O
• Molecular Weight: 222.37
• Purity: 99.67%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (11.24 mM); Clear solution
• Availability: In-stock

Source

Original product source