RV-1729

Overview

RV-1729 is an inhibitor of the phosphatidylinositol 3-kinase-δ ( PI3Kδ ). RV-1729 identifies inhibition of the PI3K isotype by quantifying the release of phosphatidylinositol 3,4, 5-triphosphate (PIP3) ( IC 50 =12 nM), showing twice the selectivity for PI3Kδ relative to PI3Kγ . RV-1729 is also 16 times more selective to PI3Kα . RV-1729 regulates immune and inflammatory responses by inhibiting PI3Kδ . RV-1729 can be used in studies of asthma and chronic obstructive pulmonary disease (COPD).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Others | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-106006
• CAS No.: 1293915-42-0
• Molecular Formula: C39H39ClN8O5
• Molecular Weight: 735.23
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source