Dehydrocorydaline nitrate (13-Methylpalmatine nitrate) is an alkaloid. Dehydrocorydaline regulates protein expression of Bax , Bcl-2 ; activates caspase-7 , caspase-8 , and inactivates PARP . Dehydrocorydaline nitrate elevates p38 MAPK activation. Anti-inflammatory and anti-cancer activities.. Dehydrocorydaline nitrate shows strong anti-malarial effects ( IC 50 =38 nM), and low cytotoxicity (cell viability > 90%) using P. falciparum 3D7 strain.
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