Bacopaside I (Standard)

Overview

Bacopaside I (Standard) is the analytical standard of Bacopaside I. This product is intended for research and analytical applications. Bacopaside I is an orally active aquaporin AQP1 inhibitor and PKC modulator with neuroprotective and anticancer activities. Bacopaside I specifically blocks the water channel and cGMP -gated ion channel activities of AQP1 without affecting AQP4 , thereby inhibiting the migration of colon cancer cells expressing AQP1. Bacopaside I activates the Akt pathway by interacting with PI3K , specifically inhibits MAO-A , effectively alleviates neuron necrosis and apoptosis induced by oxygen-glucose deprivation, reduces oxidative stress, and regulates the surface expression of neuroreceptors. When combined with Bacopaside II ( HY-N6016 ), Bacopaside I significantly reduces the viability, proliferation and invasion ability of breast cancer cells, and binds to the pregnane X receptor ( PXR ). Bacopaside I is applicable to the research of colon cancer , breast cancer , vascular dementia, cerebral ischemia and other related diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > PKC | Products > Signaling Pathways > Akt | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Pregnane X Receptor (PXR) | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Aquaporin

Product Information

• Catalog No.: HY-N4246R
• CAS No.: 382148-47-2
• Molecular Formula: C46H74O20S
• Molecular Weight: 979.13
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source