Lotusine hydroxide

Overview

Lotusine hydroxide is an orally active signaling pathway modulator and enzyme inhibitor, with an IC 50 of 30.60 μg/mL against α-amylase and an IC 50 of 36.15 μg/mL against α-glucosidase . Lotusine hydroxide inhibits the EGFR-Akt-ERK signaling pathway by reducing the levels of phosphorylated EGFR , Akt and ERK . Lotusine hydroxide induces apoptosis , triggers G 0 /G 1 cell cycle arrest and inhibits cancer cell proliferation. Lotusine hydroxide reduces lipid peroxidation and increases the activities of SOD , CAT and GPx . Lotusine hydroxide is applicable to researches related to non-small cell lung cancer , type 2 diabetes and autism spectrum disorder.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Amylases | Products > Signaling Pathways > Glycosidase

Product Information

• Catalog No.: HY-N4309A
• CAS No.: 3721-76-4
• Molecular Formula: C19H25NO4
• Molecular Weight: 331.41
• Purity: 99.56%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Availability: In-stock

Source

Original product source