Eurycomalactone

Overview

Eurycomalactone is an active quassinoid could be isolated from Eurycoma longifolia Jack . Eurycomalactone is a potent NF-κB inhibitor with an IC 50 value of 0.5 μM. Eurycomalactone inhibits protein synthesis and depletes cyclin D1. Eurycomalactone enhances radiosensitivity through arrest cell cycle at G2/M phase and delayed DNA double-strand break repair. Eurycomalactone inhibits the activation of AKT/NF-κB signaling, induces apoptosis and enhances chemosensitivity to Cisplatin ( HY-17394 ).

Application

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Product Information

• Catalog No.: HY-N4327
• CAS No.: 23062-24-0
• Molecular Formula: C19H24O6
• Molecular Weight: 348.39
• Purity: 99.74%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source