Murabutide

Overview

Murabutide is an immunomodulator and also a NOD2 receptor agonist . Murabutide enhances the signal transduction of ATR and NOD2 , mediates the activation of the DDR pathway, and thereby repairs radiation-induced DNA double-strand breaks. Murabutide inhibits radiation-induced cell apoptosis and protects cells and mice from radiation-induced toxic damage. Murabutide induces the expression and DNA-binding activity of Oct-1 in macrophages, thereby inhibiting the transcription and replication of HIV-1 . Murabutide reduces the expression levels of CD4 and CCR5 on the surface of macrophages, and induces the secretion of β-chemokines, TNF-α and IL-6 . Murabutide enhances non-specific viral resistance and targets reticuloendothelial cells. Murabutide can be used in research related to radiation-induced damage and human immunodeficiency virus type 1 infection .

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > HIV Infection | Products > Disease Areas > Sexually Transmitted Disease | Products > Disease Areas > HIV-1 Infection | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Infection | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > ATM/ATR | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > CCR | Products > Signaling Pathways > HIV | Products > Signaling Pathways > TNF Receptor

Product Information

• Catalog No.: HY-106055
• CAS No.: 74817-61-1
• Molecular Formula: C23H40N4O11
• Molecular Weight: 548.58
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source