Calcimycin

Overview

Calcimycin (A-23187) is an antibiotic and a unique divalent cation ionophore (like calcium and magnesium). Calcimycin induces Ca 2+ -dependent cell death by increasing intracellular calcium concentration. Calcimycin inhibits the growth of Gram-positive bacteria and some fungi. Calcimycin also inhibits the activity of ATPase and uncouples oxidative phosphorylation ( OXPHOS ) of mammalian cells. Calcimycin induces apoptosis and autophagy .

Application

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Product Information

• Catalog No.: HY-N6687
• CAS No.: 52665-69-7
• Molecular Formula: C29H37N3O6
• Molecular Weight: 523.62
• Purity: 99.10%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (4.77 mM); Clear solution
• Availability: In-stock

Source

Original product source