Roxindole hydrochloride

Overview

Roxindole hydrochloride (EMD 38362), an indot-alkyl-pipenidine, is a potent agonist at dopamine autoreceptors , with an affinity for the D2-like subtype in the low nanomolar range. Roxindole can be used for the research of positive and negative schizophrenic symptoms. Roxindole is a 5-HT 1A agonist and 5-HT uptake inhibitor with high affinity for 5-HT 1A (IC 50 =0.9 nM). Antipsychotic and antidepressant activities.

Application

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Product Information

• Catalog No.: HY-106100A
• CAS No.: 108050-82-4
• Molecular Formula: C23H27ClN2O
• Molecular Weight: 382.93
• Purity: 99.01%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.08 mg/mL (5.43 mM); Clear solution
• Availability: In-stock

Source

Original product source