Oligomycin B

Overview

Oligomycin B is an antibiotic that acts as a non-selective inhibitor of ATP Synthase . Oligomycin B increases mitochondrial membrane potential. Oligomycin B induces apoptosis and necrosis. Oligomycin B impairs the motility of Plasmopara viticola zoospores and induces their lysis. Oligomycin B inhibits Magnaporthe oryzae (wheat blast fungus) and suppresses the development of wheat blast. Oligomycin B reduces hyphal growth and spore germination of Botrytis cinerea , and protects Arabidopsis thaliana against Botrytis cinerea infection . Oligomycin B exacerbates cytotoxic brain edema in rats with cerebral cortical contusion, increases intracranial pressure and brain water content, and aggravates mitochondrial damage in these rats. Oligomycin B is used in studies related to grape downy mildew, traumatic brain injury, wheat blast, and gray mold.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Plant Infection | Products > Disease Areas > Botrytis Cinerea | Products > Disease Areas > Rice Blast | Products > Disease Areas > Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Anti-infection | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Neurological Disease | Products > Research Areas > Infection | Products > Signaling Pathways > ATP Synthase | Products > Signaling Pathways > Bacterial | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-N6784
• CAS No.: 11050-94-5
• Molecular Formula: C45H72O12
• Molecular Weight: 805.05
• Purity: 97.67%
• Storage: -20°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 1.25 mg/mL (1.55 mM); Clear solution
• Availability: In-stock

Source

Original product source