DTS-201

Overview

DTS-201 (CPI-0004) is a peptidic prodrug of Doxorubicin ( HY-15142A ). DTS-201, comprising the tetrapeptide portion, is cleaved by endopeptidases in the tumor environment to produce metabolites that subsequently enter the cell and are converted to active Doxorubicin . DTS-201 shows antitumoral efficacy in tumor xenograft models of prostate, breast, and lung cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Peptide-Drug Conjugates (PDCs) | Products > Signaling Pathways > Aminopeptidase

Product Information

• Catalog No.: HY-106154
• CAS No.: 274912-87-7
• Molecular Formula: C49H65N5O18
• Molecular Weight: 1012.06
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source