Licraside

Overview

Licraside, found in Glycyrrhiza glabra , is a Farnesoid X receptor ( FXR ) activator. Licraside activates FXR to induce upregulation of SHP and BSEP, regulates bile acid homeostasis, reduces elevated biliary and serum TBA, serum ALT, AST, GGT, ALP, and TBIL levels, and attenuates liver histopathological damage. Licraside inhibits factor Xa with an IC 50 of 48.54 mM. Licraside can be used for the research of cholestasis and thromboembolic diseases.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > FXR | Products > Signaling Pathways > Factor Xa

Product Information

• Catalog No.: HY-N6987
• CAS No.: 29913-71-1
• Molecular Formula: C26H30O13
• Molecular Weight: 550.51
• Purity: 99.95%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1 mg/mL (1.82 mM); Clear solution
• Availability: In-stock

Source

Original product source