7-Hydroxyflavone

Overview

7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis , with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway. 7-Hydroxyflavone inhibits PKM2 with an IC 50 of 2.12 μM. 7-Hydroxyflavone inhibits COX-2 and 5-LOX with IC 50 of 27 µg/mL and 33 µg/mL. 7-Hydroxyflavone is orally active.

Application

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Product Information

• Catalog No.: HY-N7108
• CAS No.: 6665-86-7
• Molecular Formula: C15H10O3
• Molecular Weight: 238.24
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (8.73 mM); Clear solution
• Availability: In-stock

Source

Original product source