Niraparib hydrochloride

Overview

Niraparib hydrochloride (MK-4827 hydrochloride) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with IC 50 s of 3.8 and 2.1 nM, respectively. Niraparib hydrochloride leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

Application

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Product Information

• Catalog No.: HY-10619A
• CAS No.: 1038915-64-8
• Molecular Formula: C19H21ClN4O
• Molecular Weight: 356.85
• Purity: 99.41%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.08 mg/mL (5.83 mM); Clear solution
• Availability: In-stock

Source

Original product source