Cyclic ADP-ribose

CAS No.：119340-53-3
Grade：95%
Formula：C15H21N5O13P2
M.W.：541.30

Overview

Cyclic ADP-ribose (cADPR) is a potent second messenger for calcium mobilization that is synthesized from NAD + by an ADP-ribosyl cyclase. Cyclic ADP-ribose increases cytosolic calcium mainly by Ryanodine receptor -mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels .

Application

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