13-Hydroxyisobakuchiol

Overview

13-Hydroxyisobakuchiol (Delta3,2-Hydroxylbakuchiol), an analog of Bakuchiol ( HY-N0235 ) that can be isolated from Psoralea corylifolia (L.), is a potent selective monoamine transporter inhibitor. 13-Hydroxyisobakuchiol is more selective for the dopamine transporter ( DAT ) ( IC 50 = 0.58 μM) and norepinephrine transporter ( NET ) ( IC 50 = 0.69 μM) than for the serotonin transporter ( SERT ) ( IC 50 = 312.02 μM). 13-Hydroxyisobakuchiol increases the activity of intact mice and improves the decreased activity of reserpinized mice in vivo. 13-Hydroxyisobakuchiol can be used for the research of disorders such as Parkinson's disease and depression.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Depression | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Monoamine Transporter | Products > Signaling Pathways > Dopamine Transporter

Product Information

• Catalog No.: HY-N7506
• CAS No.: 178765-49-6
• Molecular Formula: C18H24O2
• Molecular Weight: 272.38
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source