Rotigaptide (ZP123) is a novel and specific modulator of connexin 43 (Cx43) . Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Cardiovascular Disease | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Gap Junction Protein
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