Flavanomarein

Overview

Flavanomarein is a substance with cytoprotective, anti-inflammatory and antioxidant activities, with a K a of 3.064e-5 M against human Syk . Flavanomarein enhances the phosphorylation level of AKT , regulates the expression of PKC-δ, P85α, PKC-β1, Sirt1 , Bcl-2 and ICAD, and inhibits the nuclear translocation of NF-κB p65. Flavanomarein regulates EMT marker proteins, promotes the proliferation of HK-2 cells, and protects neuronal cells from 6-OHDA-induced neurotoxic damage. Flavanomarein can be used in studies related to Parkinson's disease and diabetic nephropathy.

Application

Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Hypertension | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Neurological Disease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Syk

Product Information

• Catalog No.: HY-N7675
• CAS No.: 577-38-8
• Molecular Formula: C21H22O11
• Molecular Weight: 450.39
• Purity: 99.92%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.55 mM); Clear solution
• Availability: In-stock

Source

Original product source