BIT-225

Overview

BIT-225 is an inhibitor for Vpu protein through block of Vpu ion channel, and thus inhibits the release of HIV-1 , especially in monocyte-derived macrophages ( EC 50 is 2.25 μM), without significant cytotoxicity (TC 50 is 284 μM).

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Viral Infection | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > HIV

Product Information

• Catalog No.: HY-106282
• CAS No.: 917909-71-8
• Molecular Formula: C16H15N5O
• Molecular Weight: 293.32
• Purity: 98.87%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 5 mg/mL (17.05 mM); Clear solution
• Availability: In-stock

Source

Original product source