Dehydrocurdione

Overview

Dehydrocurdione, a zedoary-derived sesquiterpene, induces heme oxygenase (HO)-1 , an antioxidative enzyme, in RAW 264.7 macrophages. Dehydrocurdione interacts with Keap1 , resulting in Nrf2 translocation followed by activation of the HO-1 E2 enhancer. Dehydrocurdione suppresses lipopolysaccharide-induced NO release, a marker of inflammation. Anti-inflammatory activity.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-N8160
• CAS No.: 38230-32-9
• Molecular Formula: C15H22O2
• Molecular Weight: 234.33
• Purity: 97%
• Storage: -20°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source